Folklore MCP
Read-only public variant and gene evidence for MCP-compatible AI clients.
Read-only MCP access to public germline variant evidence, gene profiles and literature for professional review.

Official Folklore MCP guide and public connection endpoint
Overview
What is Folklore MCP?
Read-only public variant and gene evidence for MCP-compatible AI clients.
Folklore MCP 1.7.0 connects MCP-compatible AI clients to 11 read-only tools for public germline variant evidence, gene profiles, gene-disease associations and literature. Responses include source provenance for review.
The public Streamable HTTP endpoint is https://api.helena.bio/folklore/v1/mcp. It is free to access and needs no account or API key. The interface is a tool and evidence layer; it does not run an autonomous AI agent or require a server-side LLM.
The supported variant scope is public GRCh38 nuclear germline SNVs and simple indels under 50 bp. It does not accept patient files, private case information or batch VCF uploads. Outputs require qualified professional review and are not diagnoses or treatment recommendations.
Setup guide: https://folklore.helena.bio/integrations/mcp Public adapter: https://github.com/helena-bioinformatics/folklore-mcp The Python adapter is Apache-2.0 licensed; the hosted backend and third-party data are not covered by that licence.
Platforms and languages
Folklore MCP Availability
Platforms
Languages
Capabilities
Folklore MCP Key Features
Public variant and gene evidence
11 read-only MCP tools expose public germline variant evidence, gene profiles, gene-disease associations and literature, with sources for qualified professional review. No private patient case uploads.
Plans and access
Folklore MCP Pricing
Free
The public read-only MCP endpoint is free to access and requires no account, API key or subscription. It does not accept patient files or private case data. This listing covers the public MCP interface, not a paid clinical-analysis service.
Common questions
Folklore MCP FAQs
Folklore MCP Alternatives
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